Restricted Research - Award List, Note/Discussion Page

Fiscal Year: 2018

1098  The University of Texas at El Paso  (74603)

Principal Investigator: Marc Cox

Total Amount of Contract, Award, or Gift (Annual before 2011): $ 498,487

Exceeds $250,000 (Is it flagged?): Yes

Start and End Dates: 8/1/17 - 7/31/20

Restricted Research: YES

Academic Discipline: Biological Sciences

Department, Center, School, or Institute: College of Science

Title of Contract, Award, or Gift: OR20170039 226020398A Direct Targeting of the FKBP52 Cochaperone for the Treatment of Castration-Resistant Prostate Cancer

Name of Granting or Contracting Agency/Entity: US Army Medical Research Acquisition Activity

Program Title: Military Medical Research and Development
CFDA Linked: Military Medical Research and Development


Qualifies under SAM 1.1.1. The novel drugs that are developed as a result of this project are anticipated to offer both the positive properties of the anti-androgen drugs and, through the unique mechanism of action, prevent the undesirable side effects associated with anti-androgen treatment . In addition, these novel therapies are expected to bypass mechanisms leading to disease-resistance to therapy. In addition to the identification of novel drugs, we will also generate preclinical data in cellular and animal models of prostate cancer that will be required for attracting commercial interest with the long-term goal of moving these drugs to clinical trials.

Discussion: No discussion notes


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